Partnership with Twin Health combines AI-powered precision health with fitness sessions to help reverse metabolic disease.
Fitness equipment giant Peloton has announced a partnership with Twin Health focused on managing and reversing chronic metabolic diseases. The partnership will combine Peloton’s content with Twin’s AI–driven digital twin program, integrating fitness and wellness classes into personalized care programs for people living with metabolic disease.
Designed to address the root causes of metabolic disease, Twin Health’s platform builds a “digital twin” for each member by analyzing thousands of data points from wearable devices, lab results, and meal logs. The digital twin continuously models an individual’s metabolism and provides personalized recommendations across nutrition, sleep, activity and stress management. A clinical team supports members with individualized guidance and care. Twin claims its approach has been shown to improve glycemic control and weight management while reducing reliance on medications such as GLP-1 receptor agonists and insulin.
Peloton’s contribution to the partnership centers on its library of live and on-demand fitness and wellness classes, which includes cardio, strength training, yoga and meditation. These will be integrated directly into the Twin platform, allowing the AI to recommend specific Peloton sessions based on each member’s metabolic profile and care plan, ranging from low-impact cardio to improve heart health, to yoga and meditation for stress reduction and better sleep.
“Twin Health members can benefit enormously from Peloton’s extensive library of expert-led content across many disciplines,” said Twin Chief Medical Officer Lisa Shah. “Together, we help members achieve lasting health outcomes and sustain muscle mass while safely reducing or discontinuing costly medications like GLP-1s, without rebound weight gain.”
The partnership follows the recent publication of a Cleveland Clinic–led study that found Twin Health’s approach achieved clinically significant improvements in diabetes management without medications. In the study, 71% of participants using Twin’s system achieved an A1C blood sugar test below 6.5% while discontinuing most glucose-lowering drugs. The platform’s data-driven approach enables users to make real-time adjustments to nutrition, exercise and lifestyle habits using insights generated from continuous monitoring of metrics like blood glucose, weight, blood pressure, and sleep quality.
The Peloton partnership reflects a broader strategy to expand Twin’s reach among employers and health plans. As GLP-1 use continues to grow among people with diabetes and obesity, Twin positions itself as a solution that allows organizations to manage medication costs responsibly while helping members transition toward sustained, medication-free health outcomes.
In August, Twin raised $53 million in funding led by Maj Invest of Denmark to scale its offering across major industries. The company operates on a performance-based care model, charging employers and health plans only when members achieve measurable clinical improvements such as A1C reduction, weight loss, or medication elimination. It claims to have a member retention rate of over 90% and cost savings exceeding $8,000 per member annually through reduced medication use and lower medical utilization.
“At Peloton, we have long held that movement is medicine,” said Peleton SVP Greg Hybl. “Our interest in improving people’s health outcomes is about putting that belief into action at scale, which we can accomplish with Twin Health.”
