Gut microbiome shrinks by 40% under stress: Study reveals brain-gut link


A recent study published in Cell has unveiled significant insights into the effects of chronic stress on the gut microbiome.

The research highlights how prolonged stress can cause notable changes in gut microbiome diversity, shedding light on the intricate brain-gut connection.

Using a mouse model, researchers simulated chronic stress conditions and observed their impact on the gut microbiome. They found that stress led to a marked reduction in the diversity of gut bacteria [1].

This decrease in microbial diversity was linked to increased inflammation and changes in gut permeability, which can negatively affect overall health [2].

Additionally, the study demonstrated that stress-induced alterations in the gut microbiome were associated with behavioral changes in the mice.

Specifically, the mice exhibited anxiety and depressive-like behaviors, suggesting a direct connection between gut health and mental wellbeing.

The research highlights the significance of managing stress to maintain a healthy microbiome. The study suggests that stress management strategies could be crucial for preserving microbial diversity and preventing stress-related health issues [3].

The findings reveal how chronic stress can disrupt gut microbiome health, impacting physical and mental wellbeing. This research highlights the need for effective stress management to support gut health and overall wellness.

[1] Cell. Stress-sensitive neural circuits change the gut microbiome via duodenal glands
[2] International Journal of Molecular Sciences. Influence of Foods and Nutrition on the Gut Microbiome and Implications for Intestinal Health
[3] Healthcare. The Potential Impact of Selected Bacterial Strains on the Stress Response



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