ChromaDex’s Dr Charles Brenner talks NAD+ and explains how Niagen enhances resilience against metabolic stress.
Yesterday, Longevity.Technology announced a new venture – the launch of its consumer products division, dedicated to science-backed longevity solutions. Our inaugural product, the FLT LONGEVITY supplement, showcases a unique blend of evidence-based ingredients aimed at enhancing healthspan and cellular vitality.
A major highlight of this launch is the partnership with ChromaDex, a leader in NAD+ research, to feature Niagen – ChromaDex’s proprietary nicotinamide riboside (NR) – as the supplement’s “hero” ingredient. Niagen has been shown to boost NAD+ levels, essential for cellular and metabolic functions, marking a strong foundation for the supplement’s cellular health benefits.
Longevity.Technology: Collaborating with leading suppliers and backed by human trials, Longevity.Technology emphasizes transparency and efficacy. By partnering with ChromaDex, a company known for its dedication to scientific rigor, we are demonstrating a commitment to bringing only the most effective, high-quality products to market. We sat down with one of the foremost experts in NAD+ research, Dr Charles Brenner, who is ChromaDex Chief Scientific Advisor, to find out more about his discovery that nicotinamide riboside is a precursor for NAD+, how NR affects aging and cellular health and Niagen’s potential for improving healthspan.
Dr Charles Brenner on…
Spreading the word
It’s key to talk to the public about how important NAD is, how NAD comes under attack in conditions of metabolic stress and that Niagen, the patented NR, is a safe way to boost NAD and be resilient to those conditions of metabolic stress.
Being mindful of disruption
Things that we enjoy, like being out in the sun, enjoying fresh air, listening to loud music and indulging in food and drink, can actually attack the NAD system. Many people would love to hop on a flight to Ibiza and enjoy the beach, red wine and late-night dining, but all those things can disrupt one’s NAD system. There are now seven or eight human studies showing that the NAD+ precursor NR has anti-inflammatory activity in people, which makes it a very important ingredient for healthy aging.
A wealth of clinical evidence
At this point, we’re about 20 years into using nicotinamide riboside in model systems and over a decade in humans. There are around seven or eight published clinical trials showing NR’s anti-inflammatory benefits, and looking forward, I’m particularly excited about research on cognitive impairment and neuroprotection. I’d love to see a skin healing and a fatty liver trial as well.


